High efficiency for the gastro – intestinal infections
Do not precipitated in any hardness water
INTECOL relates to antibacterial preparation of polypeptide antibiotics group.
The active ingredient is colistinsulphate – a representative of the group of polymyxins.
Colistine is active against gram-negative bacteria, including E. coli. Salmonella spp., Pasteurella spp., Pseudomonas aeruginosa, Klebsiellapneumoniae, Shigella spp. Due to its chemical structure colistin like all of polymyxinsaffects on the cytoplasmic membrane of the bacterial cell by interacting with the phospholipids. It binds to the anionic sites of the membrane and the nature of the action resembles cationic detergents. Damage to the structure of the membrane causes a change in its permeability, both inside and extracellular components, which leads to cell death. Resistancetocolistindevelopsslowly.
Pigs and poultry for therapeutic and medical and preventive purposes in diseases of bacterial etiology, their active agents are sensitive to colistine and also to E.coli, Salmonella spp., Pasteurella spp., Pseudomonas aeruginosa, Klebsiellapneumоniae, Shigella spp.
Dosage: orally for drinking water or mixed with food
Poultry: 0,5-1 ml per 1 l of water for drinking for a period of 3-5 days;
Pigs: 0,5-1 ml per 1 l of water for drinking or 0,5-1 ml per 10 kg of body weight for a period of 5-7 days.