CIPROGEN (CIPROGEN)

CONTAINS:

Ciprofloxacin
Gentamicin

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PHARMACOLOGICAL PROPERTIES:

Theuniquecombinationoffluoroquinolones
pH 4,5 solution
The bactericidal effect on Gram + and Gram bacteria
Do not precipitated in any hardness water
There is no cross-resistance with other antibiotics

MAIN CHARACTERISTICS

INDICATIONS

DOSAGE

MAIN CHARACTERISTICS

CIPROGEN – new integrated antibacterial preparation the uniqueness of action is based on a combination of two antibacterial components: fluoroquinolone and aminoglycoside. Combination of fluoroquinolones with other antimicrobial preparations usually has an additive or indifferent effect. In the case of a combination of ciprofloxacin and gentamicin observed synergistic effect, i.e. is enhanced antimicrobial action. This is especially expressed in enhancing the bactericidal properties of ciprofloxacin. This effect is due to a similar mechanism of action of both components of the preparation, which is associated with impaired synthesis of DNA and protein, respectively, in a microbial cell. This leads to the death of the microbial cells. What is important, it is not destroyed in the death of the bacterial cell itself. As a consequence, no endotoxin released from dead bacterial cells, which, in turn, leads to serious complications, up to sepsis.

INDICATION

Pigs for therapeutic purposes and broiler chickens, replacement chicks, breeding poultry with medical and preventive purposes with infectious diseases of the gastrointestinal tract, respiratory tract, urogenital system, salmonellosis, streptococcosis, necrotic enteritis, dysentery in pigs, atrophic rhinitis, gemofileze, mycoplasmosis, with mixed infections, secondary infections in viral diseases and other diseases, pathogens which are sensitive to fluoroquinolones and aminoglycosides, including: Escherihia coli, Salmonella sp., Pasteurella sp., Staphylococcus sp., Streptococcus sp., Klebsiella spp., Bordetellabronchiseptica, Corynebacteriumpyogenes, Pseudomonas aeruginosa, Campylobacter spp., Enterobacter spp., Erysipelothrix spp., Proteus spp., Brucellacanis, Actinobacillus spp., Listeria monocytogenes, Haemophilus spp., Clostridium spp., Neisseria, Serratiamarcescens, Shigella spp., Serpulina (Treponema) hyodysenteriae, Bacillus spp., and Mycoplasma spp..

DOSAGE

Dosage: orally with drinking water or mixed with feed

Poultry – 1-2 ml per 1 liter of water for drinking within 3-5 days. If salmonellosis, mixed infections and chronic forms of disease – not less than 5 days;

Pigs -1-2 ml per 1 liter of water for drinking or 1-2 ml per 10 kg of animal body weight within 5-7 days.

Eliminationperiod:

Poultry: 11 days

Pigs: 15 days